This report highlights how botanic gardens across the world are involved in a variety of projects that use biodiversity to improve human well-being and is based upon an extensive literature survey, and a multilingual survey of BGCI’s members. For the purposes of the report, BGCI has divided human well-being into four main areas: (1) improving healthcare, (2) improving nutrition, (3) alleviating financial poverty, and (4) improving community and social relations. The many case studies within the report illustrate how botanic gardens across the world are contributing to these aspects in many diverse ways.